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Cloudflare makes Python Workers GA — with Hyperdrive and first-class platform bindings

The Hyperdrive integration was the practical database unlock; the larger September 21 change is that Python Workers themselves are now GA. Cloudflare is explicitly positioning Python as a production language on Workers, with native platform bindings and framework support rather than an experimental compatibility layer.

Cloudflare Workers replaces 3MB and 10MB compressed bundle caps with one 64MiB uncompressed limit

The change makes heavier frameworks and dependency trees deployable to Workers without plan-specific compressed-size ceilings, but it also changes what builders need to measure: the operative limit is now uncompressed Total Upload rather than the gzip number they may have optimized around.